40  Impacts of Pollutants on Human Health

Pollutants reach human bodies through inhalation, ingestion, and skin contact. The route of exposure matters: airborne fine particles enter the lungs; waterborne contaminants travel through the gut; skin-contact pollutants accumulate in fat.

40.1 Air Pollutants — Health Effects

TipMajor Air Pollutants and Their Health Effects
Pollutant Source Health effect
PM2.5 Combustion, vehicles, industry Penetrates alveoli; cardiovascular and respiratory disease, lung cancer; premature death
PM10 Dust, construction Respiratory irritation, asthma
SO₂ Coal-burning Bronchitis, asthma exacerbation
NO₂ Vehicle exhaust, power plants Respiratory inflammation, asthma
CO Incomplete combustion Binds to haemoglobin (carboxyhaemoglobin); reduces oxygen delivery; fatal at high levels
Ground-level O₃ Photochemical smog Cough, chest pain, reduced lung function
Lead (Pb) Older paint, fuels, batteries Neurotoxic; reduces IQ in children
Mercury (Hg) Industrial; coal Neurological damage; Minamata disease
Asbestos Insulation, mining Asbestosis, mesothelioma
Radon Natural radioactive gas Lung cancer (second-leading cause after smoking)
VOCs Solvents, paints Headaches, eye irritation, cancer (long-term)
Indoor smoke Cooking with biomass Acute lower-respiratory infections in children
TipWHO Guidelines and Health Risk

The WHO 2021 Air Quality Guidelines tightened acceptable annual averages: - PM2.5 ≤ 5 μg/m³ - PM10 ≤ 15 μg/m³ - NO₂ ≤ 10 μg/m³

Exceeding these is associated with measurable health risk.

40.2 Water-Borne Diseases

TipMajor Water-Borne Diseases
Disease Cause Symptoms
Cholera Vibrio cholerae bacteria Severe diarrhoea, dehydration
Typhoid Salmonella typhi Sustained fever, abdominal pain
Hepatitis A and E Hepatitis virus Liver inflammation, jaundice
Diarrhoeal diseases Various pathogens Dehydration, especially in children
Polio Poliovirus Paralysis (now eradicated in India since 2014)
Schistosomiasis Parasitic flatworm Chronic infection of urinary/intestinal tract

40.3 Heavy-Metal Poisoning

TipHeavy-Metal Pollutants and Their Effects
Metal Source Health effect
Lead (Pb) Old paint, batteries, fuels Neurotoxic; affects brain development in children; anaemia
Mercury (Hg) Coal, industrial, fish Minamata disease — neurological damage
Cadmium (Cd) Batteries, electroplating, smelting Itai-Itai disease — kidney damage, bone weakening
Arsenic (As) Groundwater (West Bengal, Bangladesh) Skin lesions, cancer, black-foot disease
Chromium (Cr-VI) Tanneries, plating Cancer, skin ulcers
Aluminium Cooking utensils, smelters Linked to dementia (debated)
Nickel (Ni) Industry, batteries Skin allergy, cancer
Iron Excess in water Hemochromatosis

40.4 Famous Pollution-Linked Diseases

TipPollution Diseases — Names to Remember
Disease Cause Place of origin
Minamata Mercury poisoning (organic methyl mercury) Minamata Bay, Japan (1950s)
Itai-Itai (“It hurts! It hurts!”) Cadmium poisoning Toyama, Japan (1912)
Black-foot disease Arsenic from groundwater Taiwan, West Bengal
Pneumoconiosis / Silicosis Silica dust Mining and quarrying
Bhopal Gas Tragedy disease Methyl isocyanate (MIC) Bhopal, India (1984)
Asbestosis Asbestos fibres Asbestos workers
Mesothelioma Asbestos Asbestos workers
Byssinosis Cotton dust Textile workers
Aerotoxic syndrome (debated) Aircraft cabin air Air crew, frequent flyers
Silicosis Silica dust Mining, stone-cutting

40.5 Bioaccumulation and Biomagnification

TipTwo Working Concepts
  • Bioaccumulation — build-up of a substance within an individual organism over time (DDT in a fish’s tissue).
  • Biomagnification — concentration of substance increases up the food chain.

Tertiary consumers like top predators (eagles, sharks, humans) end up with the highest concentrations of persistent pollutants — DDT, PCBs, mercury, dioxins.

flowchart LR
  P[Plankton<br/>0.04 ppm] --> F[Small fish<br/>0.5 ppm]
  F --> L[Large fish<br/>2 ppm]
  L --> E[Eagle<br/>25 ppm]
    classDef default fill:#003366,color:#ffffff,stroke:#ffcc00,stroke-width:3px,rx:10px,ry:10px;

40.6 Pesticide Effects on Health

Persistent organic pollutants (POPs) like DDT, lindane, endosulfan persist in the environment, biomagnify up food chains, and accumulate in fatty tissue.

The Stockholm Convention on POPs (2001) lists “dirty dozen” persistent organic pollutants for elimination, including DDT (with malaria-control exemption), aldrin, dieldrin, PCBs.

40.7 Indoor Air Pollution

In India, indoor air pollution from biomass cooking (wood, dung, coal) is a major cause of respiratory disease, especially among women and children. The Pradhan Mantri Ujjwala Yojana (2016) provides LPG connections to poor households to address this.

40.8 Ozone Depletion and UV Effects

Stratospheric ozone shields humans from harmful UV-B radiation. Depletion increases:

  • Skin cancer (especially melanoma)
  • Cataracts
  • Suppression of immune system
  • Damage to crops and marine ecosystems

40.9 Practice Questions

Q 01 Minamata Medium

Minamata disease is caused by:

  • ALead poisoning
  • BMercury poisoning
  • CCadmium poisoning
  • DArsenic poisoning
View solution
Correct Option: B
Minamata disease is mercury (specifically methyl-mercury) poisoning, named after Minamata Bay, Japan, where industrial discharge contaminated fish in the 1950s.
Q 02 Itai-Itai Medium

Itai-Itai disease, characterised by bone weakening and kidney damage, is caused by:

  • ACadmium
  • BLead
  • CMercury
  • DArsenic
View solution
Correct Option: A
Itai-Itai ("It hurts! It hurts!") is caused by cadmium poisoning — first reported in Toyama, Japan in 1912.
Q 03 CO Mechanism Medium

Carbon monoxide (CO) poisoning is harmful because CO:

  • ADamages skin tissues
  • BBinds to haemoglobin and reduces oxygen delivery
  • CCauses radioactive damage
  • DDamages bones directly
View solution
Correct Option: B
CO binds 200× more strongly than O₂ to haemoglobin, forming carboxyhaemoglobin and reducing oxygen delivery.
Q 04 Black-foot Disease Hard

Black-foot disease, observed in groundwater-affected regions of West Bengal and Bangladesh, is caused by:

  • AMercury
  • BLead
  • CArsenic
  • DCadmium
View solution
Correct Option: C
Arsenic contamination in groundwater causes black-foot disease and skin/internal cancers.
Q 05 Biomagnification Medium

The increase in concentration of a persistent pollutant as it moves up the food chain is called:

  • ABioaccumulation
  • BBiomagnification
  • CBiodegradation
  • DBioremediation
View solution
Correct Option: B
Biomagnification is the rising concentration of persistent pollutants at higher trophic levels (DDT in eagles, mercury in tuna).
Q 06 PM2.5 Medium

PM2.5 is particularly dangerous to human health because:

  • AIt is highly radioactive
  • BParticles are small enough to penetrate alveoli and enter the bloodstream
  • CIt is biological in origin
  • DIt is highly inflammable
View solution
Correct Option: B
PM2.5 is fine enough (≤ 2.5 μm) to penetrate alveoli and enter the bloodstream, contributing to cardiovascular and respiratory disease.
Q 07 Asbestos Medium

Mesothelioma — a rare form of cancer affecting the lining of the lungs — is most strongly associated with exposure to:

  • ALead
  • BAsbestos
  • CCadmium
  • DMercury
View solution
Correct Option: B
Mesothelioma is strongly linked to asbestos exposure (often decades after exposure).
Q 08 Bhopal Medium

The 1984 Bhopal Gas Tragedy was caused by the leak of:

  • ACarbon monoxide
  • BMethyl isocyanate (MIC)
  • CSulphur dioxide
  • DMethane
View solution
Correct Option: B
The Bhopal Gas Tragedy (2-3 December 1984) was caused by the leak of methyl isocyanate (MIC) from the Union Carbide pesticide plant.
ImportantQuick recall
  • Pollution diseases: Minamata (Hg), Itai-Itai (Cd), Black-foot (As), Mesothelioma/Asbestosis (asbestos), Silicosis (silica), Byssinosis (cotton dust), Bhopal (MIC, 1984).
  • Bioaccumulation in individual; biomagnification up food chain.
  • CO binds haemoglobin → reduces O₂ delivery (carboxyhaemoglobin).
  • PM2.5 ≤ 2.5 μm — penetrates alveoli, enters bloodstream.
  • WHO 2021 PM2.5 guideline: ≤ 5 μg/m³ annual.
  • POPs: Stockholm Convention 2001 lists DDT, lindane, PCBs, etc.
  • PMUY (Ujjwala) 2016 — LPG to reduce indoor air pollution.
  • Stratospheric ozone depletion → skin cancer, cataracts, immune suppression.